$55

Peptides
GHK-CU
GHK-CU. Supplied as a lyophilised powder in 50mg and 100mg vials.
Supplied as lyophilised powder in 50mg, 100mg specifications. Storage: -20°C · Keep dry, avoid light. Dispatched from Sydney, Australia-wide.
Product information
About GHK-CU
Research background as published in the scientific literature. Supplied for in-vitro laboratory research only; nothing here is a claim about use in humans or animals.
GHK-Cu (Glycyl-L-histidyl-L-lysine:copper(II)) is a naturally occurring tripeptide found in human plasma, saliva, and urine. It was first isolated from human serum albumin and is known to form stable complexes with copper(II) ions, which are integral to its biological activity in research settings.
Research has examined GHK-Cu across a range of cellular and tissue-level studies, with particular focus on its role in wound healing models, skin biology, and connective tissue integrity. Studies have reported effects on fibroblast activity, angiogenesis, and the expression of genes involved in tissue repair and regeneration.
The peptide's copper-chelating properties are considered central to its research profile. Investigations into its antioxidant activity and interaction with cellular signalling pathways continue to make it a subject of interest in dermatological and regenerative research.
- Chemical Name
- Glycyl-L-histidyl-L-lysine copper
- Type
- Naturally occurring tripeptide
- Research Areas
- Collagen synthesis, tissue remodelling
- Primary Research
- Wound healing, skin biology
- Secondary Areas
- Collagen, hair follicle biology
- Key Activity
- Fibroblast stimulation, MMP modulation
- Molecular Weight
- 340.38 g/mol
- CAS Number
- 49557-75-7
- Source
- Naturally occurring — human plasma
- 01Collagen SynthesisStudies have examined GHK-Cu's role in stimulating collagen production and cross-linking, supporting connective tissue integrity in wound healing research models.
- 02Tissue RemodellingResearch has investigated GHK-Cu's influence on matrix metalloproteinases (MMPs) and tissue inhibitors, contributing to extracellular matrix remodelling pathways.
- 03Hair Follicle BiologyGHK-Cu has been studied for its effects on hair follicle size and proliferation, with research exploring its potential role in follicular growth cycle regulation.
References
- 1Pickart L et al. The human tri-peptide GHK and tissue remodeling. J Biomater Sci Polym Ed. 2008;19(8):969–88.
- 2Pickart L, Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018;19(7):1987.
- 3PubMed: pubmed.ncbi.nlm.nih.gov/?term=GHK-Cu
- 4Badenhorst D et al. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. Biomed Res Int. 2016.
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