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Melanotan 2 10mg — research peptide, lyophilised powder in a glass vial, supplied by Quantified Peptides, Sydney, Australia. For in-vitro research use only.

Peptides

Melanotan 2

Melanotan II (MT-II). Supplied as a lyophilised powder in 10mg vials.

Supplied as lyophilised powder in a 10mg specification. Storage: -20°C · Keep dry, avoid light. Dispatched from Sydney, Australia-wide.

Product information

About Melanotan 2

Melanotan II (MT-II)

Research background as published in the scientific literature. Supplied for in-vitro laboratory research only; nothing here is a claim about use in humans or animals.

Melanotan II (MT-II) is a synthetic cyclic lactam analogue of alpha-melanocyte-stimulating hormone (alpha-MSH) developed at the University of Arizona. It was designed as a more potent, metabolically stable version of alpha-MSH for research into melanogenesis and photoprotection.

Research has examined MT-II's interactions with multiple melanocortin receptors (MC1R-MC5R), with particular focus on MC1R (melanogenesis), MC3R and MC4R (energy and sexual function). It remains an investigational compound with an extensive preclinical literature and limited clinical research.

Type
Cyclic lactam alpha-MSH analogue
Research Areas
Melanogenesis, sexual function, energy metabolism
Target Receptors
MC1R, MC3R, MC4R, MC5R
Molecular Weight
1024 Da
Developer
University of Arizona
Primary Research
Melanogenesis, sexual function
Half-life
Longer than linear alpha-MSH
Research Origin
Photoprotection research
  1. 01MC1R MelanogenesisMelanotan II activates MC1R on melanocytes, stimulating melanin production through increased cAMP/PKA signalling and upregulation of tyrosinase activity. Research has examined this pathway in skin pigmentation and photoprotection research.
  2. 02MC4R & Sexual FunctionMT-II activates MC4R in the hypothalamus, which research has linked to sexual arousal pathways. Studies have examined the role of MC4R signalling in erectile function and sexual behaviour in preclinical models.
  3. 03Energy HomeostasisResearch has investigated MT-II's effects on energy balance through MC3R and MC4R activation, with studies examining food intake, energy expenditure, and body composition changes in rodent models of metabolic research.

References

  1. 1Hadley ME, Dorr RT. Melanocortin peptide therapeutics: historical milestones, clinical studies, and commercialization. Peptides. 2006;27(4):921-930.
  2. 2King SH et al. Melanocortin receptors, melanotropic peptides, and penile erection. Vitam Horm. 2007;74:379-426.
  3. 3PubMed: pubmed.ncbi.nlm.nih.gov/?term=Melanotan+II+melanocortin
  4. 4Hruby VJ et al. Cyclic lactam alpha-MSH analogues. J Med Chem. 1987;30(11):2126-2130.

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Australia-wide, plain unbranded packaging. Dispatched on business days.

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