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Thymosin Alpha-1 5mg, 10mg — research peptide, lyophilised powder in a glass vial, supplied by Quantified Peptides, Sydney, Australia. For in-vitro research use only.

Peptides

Thymosin Alpha-1

Thymosin Alpha-1 (Tα1), derived from thymosin fraction 5. Supplied as a lyophilised powder in 5mg and 10mg vials.

Supplied as lyophilised powder in 5mg, 10mg specifications. Storage: -20°C · Keep dry, avoid light. Dispatched from Sydney, Australia-wide.

Product information

About Thymosin Alpha-1

Thymosin Alpha-1 (Tα1)

Research background as published in the scientific literature. Supplied for in-vitro laboratory research only; nothing here is a claim about use in humans or animals.

Thymosin Alpha-1 (Tα1) is a 28-amino acid peptide originally isolated from thymosin fraction 5, a preparation derived from bovine thymus. It represents one of the most studied thymic peptides in immunological research.

Research has investigated its role in T-lymphocyte maturation, natural killer cell activity, and dendritic cell function. TA-1 has been the subject of clinical research in the context of immune deficiency, chronic infections, and adjuvant immunotherapy protocols in several countries, though it remains investigational in most jurisdictions.

Origin
Derived from thymosin fraction 5
Research Areas
Immune modulation, T-cell signalling
Amino Acids
28 residues
Molecular Weight
3,108 Da
CAS Number
62304-98-7
Primary Target
T-lymphocyte maturation
Key Cytokines
IL-2, IFN-γ, TNF-α
Research Status
Approved in some countries for HBV/HCV
  1. 01T-Cell ActivationThymosin Alpha-1 research has examined its role in T-lymphocyte maturation and activation. Studies investigate its effects on T-helper cell differentiation and the regulation of immune response magnitude in laboratory models.
  2. 02Dendritic Cell FunctionResearch has explored TA-1's influence on dendritic cell maturation and antigen-presenting capacity, with studies examining downstream effects on adaptive immune response initiation.
  3. 03Cytokine ModulationLaboratory investigations have examined TA-1's effects on cytokine profiles, including IL-2, interferon-gamma, and TNF-alpha, in cellular immune signalling research models.

References

  1. 1Goldstein AL et al. Thymosin Alpha1: biology and clinical applications. Expert Opin Biol Ther. 2009;9(5):593-608.
  2. 2Garaci E et al. Thymosin α1 in the treatment of cancer: from basic research to clinical application. Int J Immunopharmacol. 2000;22(12):1067-1076.
  3. 3PubMed: pubmed.ncbi.nlm.nih.gov/?term=thymosin+alpha+1
  4. 4Liu F et al. Thymosin alpha 1: Biological activities, mechanisms of action, and clinical applications. Curr Protein Pept Sci. 2020;21(7):653-668.

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