$70

Peptides
Thymosin Alpha-1
Thymosin Alpha-1 (Tα1), derived from thymosin fraction 5. Supplied as a lyophilised powder in 5mg and 10mg vials.
Supplied as lyophilised powder in 5mg, 10mg specifications. Storage: -20°C · Keep dry, avoid light. Dispatched from Sydney, Australia-wide.
Product information
About Thymosin Alpha-1
Thymosin Alpha-1 (Tα1)
Research background as published in the scientific literature. Supplied for in-vitro laboratory research only; nothing here is a claim about use in humans or animals.
Thymosin Alpha-1 (Tα1) is a 28-amino acid peptide originally isolated from thymosin fraction 5, a preparation derived from bovine thymus. It represents one of the most studied thymic peptides in immunological research.
Research has investigated its role in T-lymphocyte maturation, natural killer cell activity, and dendritic cell function. TA-1 has been the subject of clinical research in the context of immune deficiency, chronic infections, and adjuvant immunotherapy protocols in several countries, though it remains investigational in most jurisdictions.
- Origin
- Derived from thymosin fraction 5
- Research Areas
- Immune modulation, T-cell signalling
- Amino Acids
- 28 residues
- Molecular Weight
- 3,108 Da
- CAS Number
- 62304-98-7
- Primary Target
- T-lymphocyte maturation
- Key Cytokines
- IL-2, IFN-γ, TNF-α
- Research Status
- Approved in some countries for HBV/HCV
- 01T-Cell ActivationThymosin Alpha-1 research has examined its role in T-lymphocyte maturation and activation. Studies investigate its effects on T-helper cell differentiation and the regulation of immune response magnitude in laboratory models.
- 02Dendritic Cell FunctionResearch has explored TA-1's influence on dendritic cell maturation and antigen-presenting capacity, with studies examining downstream effects on adaptive immune response initiation.
- 03Cytokine ModulationLaboratory investigations have examined TA-1's effects on cytokine profiles, including IL-2, interferon-gamma, and TNF-alpha, in cellular immune signalling research models.
References
- 1Goldstein AL et al. Thymosin Alpha1: biology and clinical applications. Expert Opin Biol Ther. 2009;9(5):593-608.
- 2Garaci E et al. Thymosin α1 in the treatment of cancer: from basic research to clinical application. Int J Immunopharmacol. 2000;22(12):1067-1076.
- 3PubMed: pubmed.ncbi.nlm.nih.gov/?term=thymosin+alpha+1
- 4Liu F et al. Thymosin alpha 1: Biological activities, mechanisms of action, and clinical applications. Curr Protein Pept Sci. 2020;21(7):653-668.
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