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Selank 10mg — research peptide, lyophilised powder in a glass vial, supplied by Quantified Peptides, Sydney, Australia. For in-vitro research use only.

Peptides

Selank

Thr-Lys-Pro-Arg-Pro-Gly-Pro (Tuftsin analogue), synthetic — Institute of Molecular Genetics, Russia. Supplied as a lyophilised powder in 10mg vials.

Supplied as lyophilised powder in a 10mg specification. Storage: -20°C · Keep dry, avoid light. Dispatched from Sydney, Australia-wide.

Product information

About Selank

Thr-Lys-Pro-Arg-Pro-Gly-Pro (Tuftsin analogue)

Research background as published in the scientific literature. Supplied for in-vitro laboratory research only; nothing here is a claim about use in humans or animals.

Selank is a synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) developed by the Institute of Molecular Genetics of the Russian Academy of Sciences as a stable analogue of the endogenous immunomodulatory peptide tuftsin. It has been studied for over two decades for its anxiolytic-like properties in preclinical models.

Unlike benzodiazepines, Selank research has not demonstrated sedation or dependency in animal models. Studies have explored its effects on GABAergic, serotonergic, and dopaminergic systems, as well as its influence on BDNF expression and immune-brain communication pathways.

Origin
Synthetic — Institute of Molecular Genetics, Russia
Research Areas
Anxiolytic mechanisms, BDNF modulation, immune-brain axis
Amino Acids
7 residues (Thr-Lys-Pro-Arg-Pro-Gly-Pro)
CAS Number
129954-34-3
Molecular Weight
751.9 g/mol
Research Institution
Inst. of Molecular Genetics, RAS
Key Pathways
GABA · Serotonin · BDNF · Tuftsin
Primary Research
Anxiolytic mechanisms, cognition
Research Models
Rodent anxiety and stress models
  1. 01GABAergic & Serotonergic ModulationResearch has investigated Selank's interaction with GABAergic and serotonergic neurotransmitter systems. Studies propose it may potentiate GABA-A receptor activity without binding directly to the benzodiazepine site, differentiating it from classical anxiolytics.
  2. 02BDNF ExpressionLaboratory studies have examined Selank's effects on BDNF (brain-derived neurotrophic factor) expression. Research in animal models suggests it may upregulate BDNF in hippocampal and cortical tissues, supporting neuroplasticity pathway investigation.
  3. 03Immune-Brain Axis ResearchSelank is derived from tuftsin, an endogenous immunomodulatory peptide. Research has examined its dual role in both CNS signalling and immune modulation, investigating the peptide's influence on cytokine profiles and coagulation pathways.

References

  1. 1Semenova TP et al. Selank effects on cognitive function in rats. Bull Exp Biol Med. 2010;150(3):306-9.
  2. 2Zozulya AA et al. Heptapeptide Selank as anxiolytic. Bull Exp Biol Med. 2001;131(6):523-5.
  3. 3PubMed: pubmed.ncbi.nlm.nih.gov/?term=Selank+peptide
  4. 4Kozlovskaya MM et al. Selank pharmacology. Eksperimental'naya i Klinicheskaya Farmakologiya. 2002.

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Australia-wide, plain unbranded packaging. Dispatched on business days.

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