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Peptides
Adalank 10mg — research peptide, lyophilised powder in a glass vial, supplied by Quantified Peptides, Sydney, Australia. For in-vitro research use only.

Peptides

Adalank

Adalank (Ala-Lys). Supplied as a lyophilised powder in 10mg vials.

Supplied as lyophilised powder in a 10mg specification. Storage: -20°C · Keep dry, avoid light. Dispatched from Sydney, Australia-wide.

Product information

About Adalank

Adalank (Ala-Lys)

Research background as published in the scientific literature. Supplied for in-vitro laboratory research only; nothing here is a claim about use in humans or animals.

Adalank is a synthetic dipeptide (Ala-Lys) developed within the Russian peptide bioregulator research programme led by Khavinson et al. at the Saint Petersburg Institute of Bioregulation and Gerontology. It belongs to a class of short peptide bioregulators designed to modulate tissue-specific gene expression.

Research has examined Adalank's effects on neuronal models, investigating its potential role in cognitive function and neuroprotection. As a dipeptide, it is small enough to cross cellular barriers and is proposed to interact with DNA regulatory regions to influence gene transcription relevant to brain tissue function.

Type
Dipeptide — bioregulator
Research Areas
Cognitive function, neuroprotection, ageing
Sequence
Ala-Lys (dipeptide)
Molecular Weight
~217 Da
Research Programme
Khavinson — St Petersburg Institute
Research Focus
Cognitive function, neuroprotection
Proposed Mechanism
Gene transcription modulation
Research Models
Neuronal cell culture
  1. 01Neurotrophin ModulationAdalank research has examined effects on neurotrophin expression, with studies investigating whether this dipeptide influences BDNF and NGF signalling in neuronal cell models relevant to cognitive research.
  2. 02NeuroprotectionLaboratory investigations have examined Adalank's cytoprotective properties in neuronal models subjected to oxidative stress, exploring effects on cell viability, mitochondrial membrane potential, and apoptotic markers.
  3. 03Gene ExpressionResearch has investigated Adalank's influence on gene transcription in cortical and hippocampal cell models, with studies examining expression changes in genes associated with synaptic plasticity and neuroprotective pathways.

References

  1. 1Khavinson VK et al. Short peptides regulate gene expression. Bull Exp Biol Med. 2013;155(3):317-319.
  2. 2Khavinson VK, Malinin VV. Gerontological Aspects of Genome Peptide Regulation. Karger, Basel. 2005.
  3. 3PubMed: pubmed.ncbi.nlm.nih.gov/?term=Adalank+peptide
  4. 4Khavinson VK et al. Peptide regulation of gene expression and protein synthesis in brain neurons. Neuro Endocrinol Lett. 2002;23(S3):11-144.

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