$80

Peptides
Adalank
Adalank (Ala-Lys). Supplied as a lyophilised powder in 10mg vials.
Supplied as lyophilised powder in a 10mg specification. Storage: -20°C · Keep dry, avoid light. Dispatched from Sydney, Australia-wide.
Product information
About Adalank
Adalank (Ala-Lys)
Research background as published in the scientific literature. Supplied for in-vitro laboratory research only; nothing here is a claim about use in humans or animals.
Adalank is a synthetic dipeptide (Ala-Lys) developed within the Russian peptide bioregulator research programme led by Khavinson et al. at the Saint Petersburg Institute of Bioregulation and Gerontology. It belongs to a class of short peptide bioregulators designed to modulate tissue-specific gene expression.
Research has examined Adalank's effects on neuronal models, investigating its potential role in cognitive function and neuroprotection. As a dipeptide, it is small enough to cross cellular barriers and is proposed to interact with DNA regulatory regions to influence gene transcription relevant to brain tissue function.
- Type
- Dipeptide — bioregulator
- Research Areas
- Cognitive function, neuroprotection, ageing
- Sequence
- Ala-Lys (dipeptide)
- Molecular Weight
- ~217 Da
- Research Programme
- Khavinson — St Petersburg Institute
- Research Focus
- Cognitive function, neuroprotection
- Proposed Mechanism
- Gene transcription modulation
- Research Models
- Neuronal cell culture
- 01Neurotrophin ModulationAdalank research has examined effects on neurotrophin expression, with studies investigating whether this dipeptide influences BDNF and NGF signalling in neuronal cell models relevant to cognitive research.
- 02NeuroprotectionLaboratory investigations have examined Adalank's cytoprotective properties in neuronal models subjected to oxidative stress, exploring effects on cell viability, mitochondrial membrane potential, and apoptotic markers.
- 03Gene ExpressionResearch has investigated Adalank's influence on gene transcription in cortical and hippocampal cell models, with studies examining expression changes in genes associated with synaptic plasticity and neuroprotective pathways.
References
- 1Khavinson VK et al. Short peptides regulate gene expression. Bull Exp Biol Med. 2013;155(3):317-319.
- 2Khavinson VK, Malinin VV. Gerontological Aspects of Genome Peptide Regulation. Karger, Basel. 2005.
- 3PubMed: pubmed.ncbi.nlm.nih.gov/?term=Adalank+peptide
- 4Khavinson VK et al. Peptide regulation of gene expression and protein synthesis in brain neurons. Neuro Endocrinol Lett. 2002;23(S3):11-144.
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