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Peptides
Cerebrolysin 60mg — research peptide, lyophilised powder in a glass vial, supplied by Quantified Peptides, Sydney, Australia. For in-vitro research use only.

Peptides

Cerebrolysin

Cerebrolysin (FPF-1070). Supplied as a lyophilised powder in 60mg vials.

Supplied as lyophilised powder in a 60mg specification. Storage: -20°C · Keep dry, avoid light. Dispatched from Sydney, Australia-wide.

Product information

About Cerebrolysin

Cerebrolysin (FPF-1070)

Research background as published in the scientific literature. Supplied for in-vitro laboratory research only; nothing here is a claim about use in humans or animals.

Cerebrolysin is a standardised mixture of low-molecular-weight neuropeptides and amino acids derived from purified porcine brain proteins. It contains approximately 25% active peptide fragments and 75% free amino acids.

Research has focused on its neurotrophic properties, with studies demonstrating BDNF-like and NGF-like activity in cell and animal models. Clinical investigations have examined its effects in stroke rehabilitation, vascular dementia, and Alzheimer's disease, with varying results across trial designs.

Type
Porcine brain-derived peptide mixture
Research Areas
Neuroprotection, neuroplasticity, cognitive research
Active Peptides
~25% by weight
CAS
12656-61-0 (complex mixture)
Key Activity
BDNF-like, NGF-like
Primary Research
Stroke, neurodegeneration
Clinical Trials
Numerous Phase 2/3 in dementia
  1. 01BDNF-like ActivityCerebrolysin contains low-molecular-weight peptides that research has shown to mimic the effects of brain-derived neurotrophic factor (BDNF). Studies examine effects on neuronal survival, differentiation, and synaptic plasticity.
  2. 02NeuroprotectionResearch has investigated Cerebrolysin's neuroprotective properties in models of ischaemia, excitotoxicity, and oxidative stress, examining effects on neuronal cell viability and inflammatory cascade modulation.
  3. 03NeuroplasticityLaboratory studies have examined Cerebrolysin's influence on dendritic branching, synaptogenesis, and long-term potentiation in neuronal cell and animal models of cognitive function.

References

  1. 1Rockenstein E et al. Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation. J Neurosci Res. 2006;83(7):1252-1261.
  2. 22Álvarez XA et al. Neurotrophic effects of Cerebrolysin in patients with dementia. Drugs Today. 2011;47(9):703-718.
  3. 3PubMed: pubmed.ncbi.nlm.nih.gov/?term=Cerebrolysin+neuroprotection
  4. 4Chen CC et al. Cerebrolysin in the treatment of acute ischaemic stroke. Cochrane Database Syst Rev. 2020.

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