$100

Peptides
GHRP-6
Growth Hormone Releasing Peptide-6. Supplied as a lyophilised powder in 10mg vials.
Supplied as lyophilised powder in a 10mg specification. Storage: -20°C · Keep dry, avoid light. Dispatched from Sydney, Australia-wide.
Product information
About GHRP-6
Growth Hormone Releasing Peptide-6
Research background as published in the scientific literature. Supplied for in-vitro laboratory research only; nothing here is a claim about use in humans or animals.
GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide that acts as a potent agonist at the GHS-R1a receptor, the endogenous receptor for ghrelin. It was one of the first synthetic GH secretagogues developed and has been extensively studied as a research tool for examining GH secretory dynamics.
Research has demonstrated that GHRP-6 stimulates GH release synergistically with GHRH analogues when combined, making it a commonly used tool peptide in GH axis research. Additional studies have examined its appetite-stimulating properties and potential cytoprotective effects in cardiac and liver injury models.
- Type
- Hexapeptide GHS-R1a agonist
- Research Areas
- GH secretion, appetite, cytoprotection
- Amino Acids
- 6 residues (hexapeptide)
- Target
- GHS-R1a (ghrelin receptor)
- Molecular Weight
- 873 Da
- CAS Number
- 87616-84-0
- GH Stimulation
- Potent — synergistic with GHRH
- Cortisol Effect
- Yes — more than Ipamorelin
- Research Area
- GH axis, cytoprotection
- 01GHS-R1a ActivationGHRP-6 is a synthetic hexapeptide that activates the growth hormone secretagogue receptor 1a (GHS-R1a), the ghrelin receptor. Research examines pulsatile GH release stimulation and downstream somatotroph activity in pituitary models.
- 02Ghrelin MimicryGHRP-6 mimics ghrelin's action at GHS-R1a, with research examining both GH-releasing and appetite-stimulating effects. Unlike Ipamorelin, GHRP-6 studies show more pronounced cortisol and prolactin co-stimulation.
- 03CytoprotectionResearch has examined GHRP-6's cytoprotective effects independently of GH release, with studies investigating cardioprotective and hepatoprotective properties in tissue injury models through GHS-R1a-independent pathways.
References
- 1Bowers CY et al. On the in vitro and in vivo activity of growth hormone releasing peptide-6. J Clin Endocrinol Metab. 1991;73(6):1326-1330.
- 2Isgaard J et al. GHRP-6 protects the heart against ischaemia-reperfusion injury. Regul Pept. 2010;165(2-3):145-150.
- 3PubMed: pubmed.ncbi.nlm.nih.gov/?term=GHRP-6
- 4Howard AD et al. A receptor in pituitary and hypothalamus that functions in growth hormone release. Science. 1996;273(5277):974-977.
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